Asthma Management Handbook
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Table. Categories applied to non-systematic review clinical questions by working groups

Category Considerations Action Output
High-priority Questions for which a structured literature search warranted due to clinical relevance and genuine uncertainty on interpretation of current evidence Researcher (medical writer or volunteer working group member) conducts structured literature search and provides evidence report (search strategy, evidence table) Recommendations based on selected evidence
Sufficient existing evidence Clinical questions for which reliable evidence-based guidance exists (e.g. Cochrane reviews, other recent reviews internationally recognised clinical practice guidelines, systematic reviews undertaken by other guideline groups), and for which additional literature searches are unlikely to influence the working group’s guidance Medical writer prepares summary of sources identified by working group Recommendations adapted from existing guidance
Recommendations based on selected evidence
Other Questions for which a formal literature search is unlikely to affect guidance and on which it is appropriate to base guidance on subjective opinion Working group develops consensus recommendations based on clinical experience and identified evidence Consensus recommendations

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