Asthma Management Handbook

Abbreviations and explanations of terms

ACE inhibitors

angiotensin converting enzyme inhibitors

aspirin-exacerbated respiratory disease

also called aspirin/NSAID-intolerant asthma or aspirin-sensitive asthma

Asthma Score

also called 'Asthma Control Test'

beclometasone

or beclomethasone

Category A

[Therapeutic Goods Administration pregnancy safety category A] drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the foetus having been observed.

Category B1

[Therapeutic Goods Administration pregnancy safety category B1] drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human foetus having been observed. Studies in animals have not shown evidence of an increased occurrence of foetal damage.

Category B2

[Therapeutic Goods Administration pregnancy safety category B2] drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human foetus having been observed. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of foetal damage.

Category B3

[Therapeutic Goods Administration pregnancy safety category B3] drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human foetus having been observed. Studies in animals have shown evidence of an increased occurrence of foetal damage, the significance of which is considered uncertain in humans.

Category C

[Therapeutic Goods Administration pregnancy safety category C] drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human foetus or neonate without causing malformations. These effects may be reversible.

CFC

chlorofluorocarbon

COPD

chronic obstructive pulmonary disease

COX

cyclo-oxygenase

ED

emergency department

EIB

exercise-induced bronchoconstriction

Evidence-based recommendation (Grade A)

Body of evidence can be trusted to guide practice

Evidence-based recommendation (Grade B)

Body of evidence can be trusted to guide practice in most situations

Evidence-based recommendation (Grade C)

Body of evidence provides some support for recommendation but care should be taken in its application

Evidence-based recommendation (Grade D)

Body of evidence is weak and recommendation must be applied with caution

FEV

forced expiratory volume over a specified time period:

FEV1: forced expiratory volume over one second
FEV6: forced expiratory volume over six seconds

flare-up

exacerbation

flare-ups

exacerbations

FSANZ

Food Standards Australia and New Zealand

FVC

forced vital capacity

GORD

gastro-oesophageal reflux disease

HFA

formulated with hydrofluoroalkane (CFC-free) propellant

ICS

inhaled corticosteroid

ICU

intensive care unit

IgE

Immunoglobulin E

IL

interleukin

IV

intravenous

LABA

long-acting beta2-adrenergic receptor agonist

LAMA

long-acting muscarinic antagonist (long-acting anticholinergic bronchodilator)

LTRA

leukotriene receptor antagonist

MBS

Medical Benefits Scheme

NHMRC

National Health and Medical Research Council

NIPPV

non-invasive positive pressure ventilation

NSAIDs

nonsteroidal anti-inflammatory drugs

occupational asthma

new-onset asthma due to workplace factors

OCS

oral corticosteroids

OSA

Obstructive sleep apnoea

PaCO

carbon dioxide partial pressure on blood gas analysis

PaO

oxygen partial pressure on blood gas analysis

PBS

Pharmaceutical Benefits Scheme

PEF

peak expiratory flow

pMDI

pressurised metered-dose inhaler or 'puffer'

PPE

personal protective equipment

preventer

sometimes called controller

SABA

short-acting beta2-adrenergic receptor agonist

SAMA

short-acting muscarinic antagonist (short-acting anticholinergic bronchodilator)

TGA

Therapeutic Goods Administration

upper airway dysfunction

also known as vocal cord dysfunction

work-exacerbated asthma

worsening of asthma control due to workplace factors