Immediate treatment of acute asthma in adults and adolescents in primary care

 Mild–moderately severeSevereLife-threatening
Assessment

All of:

Can walk, speak whole sentences in one breath

SpO2 (room air) >94%

Any of:

Unable to complete sentences in one breath due to breathlessness

Use of accessory muscles of neck or intercostal muscles/tracheal tug/subcostal recession during inspiration

Obvious respiratory distress

SpO2 (room air) ≤94%

Any of:

Reduced consciousness/collapse, exhaustion

Cyanosis

Poor respiratory effort

SpO2 (room air) <92%

Poor respiratory effort, soft/absent breath sounds

 

TriageManage in place

Arrange transfer to acute care


 

Immediate treatment

Give salbutamol 4–12 actuations (100 microg per actuation) via pMDI and spacer (tidal breathing method)

Give salbutamol 12 actuations (100 microg per actuation) via pMDI and spacer (tidal breathing).

If patient cannot use spacer, 5 mg salbutamol nebule via nebuliser (if available)

Start oxygen supplementation if SpO(room air) <92%.* Titrate to target SpO92–96%

Without nebuliser: Give salbutamol 12 actuations (100 microg per actuation) via pMDI and spacer ± mask (tidal breathing).

With nebuliser: Give salbutamol 2 x 5 mg nebules via continuous nebulisation driven by oxygen: SpOtarget 92–96%*

Continued treatmentRepeat salbutamol 4–12 actuations every 20–30 minutes for the first hour, if needed (sooner if needed)Repeat salbutamol 12 actuations at least every 20 minutes for first hour (3 doses)Maintain SpOto target 92–96%*

Additional information

SpO2: oxygen saturation measured by pulse oximetry; *88–92% for patients at risk of hypercapnoea