Asthma Management Handbook

Clinical questions for systematic review

Systematic review of allergen avoidance strategies and asthma outcomes

Clinical question for literature search:

Is allergen avoidance effective in improving asthma control? Which allergen avoidance strategies are most effective in controlling symptoms of asthma?

Recommendations based on this body of evidence:

Systematic review of GORD treatment and asthma outcomes

Clinical question for literature search:

Does GORD treatment/therapy (H2-receptor antagonists, proton pump inhibitors, anti-reflux surgery, acid suppressive therapy) improve asthma control in people with asthma (adults/children) who have a clinical diagnosis of GORD?

Recommendations based on this body of evidence:

Systematic review of physical activity and asthma outcomes

Clinical question for literature search:

Does planned physical activity (e.g. structured physical activity programs, exercise training/intervention such as swimming, running, cycling) improve asthma outcomes (e.g. lung function, asthma control, quality of life, effect on exercise-induced bronchoconstriction), compared with no planned physical activity (e.g. usual clinical care, treatment regimens that do not included planned physical activity) in children and adults with asthma?

Recommendations based on this body of evidence:

Systematic review of asthma treatment and pregnancy outcomes

Clinical question for literature search:

What are the effects of (1) asthma and (2) asthma treatment on pregnancy outcomes?

For example:

  • Does effective asthma control improve pregnancy outcomes [maternal, foetal] in women with asthma?
  • Does poorly controlled asthma [evidenced by exacerbations, acute asthma episodes, emergency visits] affect pregnancy outcomes in women with asthma?
  • Does asthma treatment affect pregnancy outcomes [maternal, foetal] in women with asthma?

Recommendations based on this body of evidence:

Systematic review of weight loss and asthma outcomes

Clinical question for literature search:

Does weight loss improve asthma control in overweight/obese patients with asthma?

  • Does a weight loss intervention or program (e.g. diet, exercise, physical activity) improve asthma outcomes in obese/overweight patients (adults/children) with asthma, compared with usual care?
  • Does surgically induced weight loss (e.g. gastric bypass, gastric banding, bariatric surgery) improve asthma outcomes in obese patients with asthma, compared with usual care?

Recommendations based on this body of evidence: